interactive matrix language (iml) module Search Results


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Molecular Dynamics Inc di-dha-pc ddpc
No influence of phototoxicity on retinal disruption in the LPAAT3-KO mice. Mice at 1–3 weeks old were maintained under dark conditions for 2 weeks, and their retinal layers were analyzed. OS/IS and <t>ONL</t> from LPAAT3-KO retinas were lower than those of WT retinas, with similar results to those under normal light/dark cycle conditions. LPAAT3-KO mice were not influenced by phototoxicity under the conditions. Four independent experiments were performed with similar results (hematoxylin and eosin staining). Results are expressed as the mean ± S.E. p value, Mann-Whitney U test. Experimental numbers of OS/IS were n = 5 in WT and n = 8 in LPAAT3-KO retinas from each four mice. ONL and <t>INL</t> were n = 8 from four retinas from each mouse.
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Image Search Results


No influence of phototoxicity on retinal disruption in the LPAAT3-KO mice. Mice at 1–3 weeks old were maintained under dark conditions for 2 weeks, and their retinal layers were analyzed. OS/IS and ONL from LPAAT3-KO retinas were lower than those of WT retinas, with similar results to those under normal light/dark cycle conditions. LPAAT3-KO mice were not influenced by phototoxicity under the conditions. Four independent experiments were performed with similar results (hematoxylin and eosin staining). Results are expressed as the mean ± S.E. p value, Mann-Whitney U test. Experimental numbers of OS/IS were n = 5 in WT and n = 8 in LPAAT3-KO retinas from each four mice. ONL and INL were n = 8 from four retinas from each mouse.

Journal: The Journal of Biological Chemistry

Article Title: Docosahexaenoic acid preserves visual function by maintaining correct disc morphology in retinal photoreceptor cells

doi: 10.1074/jbc.M117.790568

Figure Lengend Snippet: No influence of phototoxicity on retinal disruption in the LPAAT3-KO mice. Mice at 1–3 weeks old were maintained under dark conditions for 2 weeks, and their retinal layers were analyzed. OS/IS and ONL from LPAAT3-KO retinas were lower than those of WT retinas, with similar results to those under normal light/dark cycle conditions. LPAAT3-KO mice were not influenced by phototoxicity under the conditions. Four independent experiments were performed with similar results (hematoxylin and eosin staining). Results are expressed as the mean ± S.E. p value, Mann-Whitney U test. Experimental numbers of OS/IS were n = 5 in WT and n = 8 in LPAAT3-KO retinas from each four mice. ONL and INL were n = 8 from four retinas from each mouse.

Article Snippet: The abbreviations used are: DHA docosahexaenoic acid ERG electroretinogram PE phosphatidylethanolamine RPE retinal pigment epithelial LPC lysophosphatidylcholine PA phosphatidic acid PC phosphatidylcholine PL-DHA DHA-containing phospholipid OS outer segment PL phospholipid DLS dynamic light scattering MD molecular dynamics PS phosphatidylserine PG phosphatidylglycerol PI phosphatidylinositol AA arachidonic acid DOPC di-oleoyl-PC DAPC di-arachidonoyl-PC DDPC di-DHA-PC (DDPC) DOPE di-oleoyl-PE DDPE di-DHA-PC ONL outer nuclear layer INL inner nuclear layer IS inner segment TEM transmission electron microscopy DPPC dipalmitoyl-PC ANOVA analysis of variance cd candela.

Techniques: Disruption, Staining, MANN-WHITNEY